Knee osteoarthritis is a type of joint problem that happens when the knee joint gets worn out over time. The most common form is primary osteoarthritis, typically associated with aging and wear-and-tear on the knee joint.  It is most common in older people and occurs because the cushioning between the bones in the knee breaks down. This causes pain, stiffness, and makes it harder to move your knee.

Secondary osteoarthritis results from underlying conditions or injuries that affect the knee joint, such as previous trauma, inflammatory diseases like rheumatoid arthritis, or congenital abnormalities. This type may develop earlier in life and progress more rapidly than primary osteoarthritis due to the initial damage to the joint.

Post-traumatic osteoarthritis arises following a significant knee injury, such as ligament tears or fractures, which can disrupt the joint’s structure and accelerate cartilage breakdown. Athletes and individuals with physically demanding occupations are particularly susceptible to this type.

Additionally, there’s idiopathic osteoarthritis, where the exact cause remains unknown despite thorough examination. This type often presents similarly to primary osteoarthritis but may have underlying factors yet to be identified.

It is important to know exactly what kind of knee arthritis you have so you can figure out the best ways to deal with it. This might mean taking medicine, doing exercises, changing how you live, or even having surgery to help with the pain and keep your knee working right.

Knee osteoarthritis, a degenerative joint condition, can significantly impact mobility and quality of life. Understanding its causes sheds light on prevention and management strategies:

• Sports Injuries: Repetitive stress on the knee joint from high-impact sports like football or basketball can lead to cartilage wear and tear, increasing the risk of osteoarthritis over time.
• Falls: Sudden falls, especially in older individuals, can result in trauma to the knee joint, accelerating cartilage degeneration and predisposing to osteoarthritis development.
• Car Accidents: Traumatic injuries sustained in car accidents, such as fractures or ligament tears, can disrupt the knee joint’s stability and contribute to the onset of osteoarthritis.
• Joint Affecting Health Conditions: Certain health conditions like rheumatoid arthritis or gout can indirectly affect the knee joint, leading to inflammation and cartilage damage, ultimately culminating in osteoarthritis.
• Obesity: Excessive body weight places additional stress on the knee joint, accelerating the degeneration of cartilage and increasing the likelihood of developing osteoarthritis.
• Genetics: Genetic predisposition can play a role in the development of knee osteoarthritis, influencing factors such as cartilage strength and joint alignment.
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When doctors diagnose knee osteoarthritis, they do a thorough check to make sure it is really, what’s causing the pain and not something else. They look at everything to be sure.

1. X-rays: X-rays are commonly used to diagnose knee osteoarthritis. They can reveal narrowing of joint space, the presence of osteophytes (bone spurs), and changes in bone density characteristic of osteoarthritis.
2. MRI (Magnetic Resonance Imaging): MRI scans are super-detailed pictures that show us all the ins and outs of our bodies, including things like muscles, cartilage, and bones. They are helpful for spotting early signs of osteoarthritis, like when the cartilage starts to wear away, and they can also tell us how bad the damage is to our joints and if there’s any inflammation going on.
3. Blood Tests: While there isn’t a particular blood test for confirming osteoarthritis, blood tests can assist in ruling out other conditions that might seem like it, such as rheumatoid arthritis or gout, just like how a student uses different methods to eliminate incorrect answers when solving a problem.
4. Joint Fluid Analysis: Analysing the fluid extracted from the knee joint can help confirm the diagnosis of osteoarthritis and rule out other conditions like infection or crystal-induced arthritis. In osteoarthritis, the fluid typically shows signs of inflammation and may contain higher levels of certain proteins.

By using a mix of these tests and carefully examining symptoms and medical history, doctors can correctly identify knee osteoarthritis in patients and come up with the right treatment plan.

Knee osteoarthritis is a type of joint problem that can really affect how well you can move and how you feel every day. It can make your knees hurt a lot and might make it hard to do things like walking or playing sports. It is important to know what signs to look out for so you can get help and make sure it doesn’t stop you from doing all the things you love. Individuals affected by this condition often experience:

• Pain: Persistent discomfort, especially during movement or weight-bearing activities, is a hallmark symptom of knee osteoarthritis. The pain may worsen with prolonged activity and ease with rest.
• Stiffness: Stiffness in the knee joint, particularly after periods of inactivity such as waking up in the morning or sitting for an extended period, is common. This stiffness can gradually improve with movement.
• Tenderness: The affected area may feel tender to the touch, indicating inflammation and irritation within the joint.
• Loss of flexibility: Reduced range of motion in the knee joint is another characteristic feature, making it difficult to fully bend or straighten the leg.
• Bone spurs: Over time, the body may form bony outgrowths called bone spurs around the edges of the affected joint, contributing to further pain and limited mobility.
• Swelling: Inflammation within the joint often leads to swelling, visible as increased size or puffiness around the knee.
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PRP Treatment is becoming a prior choice for treating many medical conditions including knee osteoarthritis. If you are taking the treatment from Global Regenx, then it will be a three days procedure which includes:

Day 1:

• Pick you up from the airport to the hospital
• Discuss session with doctor 
• Admission will be done
• Obtaining supportive therapies

Day 2:

• Beginning of PRP treatment 
• Some supportive therapies will provided
• Another counselling session

Day 3:

• Supporting therapies continues.
• Getting involved in physiotherapy sessions.
• Completion of necessary paperwork.
• Get back to the airport by our transportation service.

Note To Remember

• Bring your Valid Identification Card (PAN Card/Passport/Driving License) for the admission process
• Also take hard copies of patient’s medical history

Knee osteoarthritis (OA) is a kind of joint problem that lots of people around the world have. It happens when the cushion-like cartilage in your knee wears away, causing pain and swelling. Traditional treatments just try to ease the pain, but there’s a new idea called Platelet-Rich Plasma (PRP) therapy.  It helps your knee heal better and reduces the swelling too.

PRP treatment involves drawing a patient’s blood and centrifuging it to isolate platelets rich in growth factors. These growth factors stimulate tissue repair and regeneration when injected into the affected joint. In knee OA, PRP injections have shown efficacy in alleviating pain, improving function, and potentially slowing disease progression.

Studies have found that PRP therapy not only makes knee OA symptoms better; it also helps fix what’s wrong with the joint. When you get PRP, it sends a strong dose of growth factors right to the damaged area. This helps fix the cartilage and stops swelling, giving long-lasting benefits that go beyond just feeling better for a little while.

Moreover, PRP treatment is minimally invasive and associated with minimal adverse effects compared to surgical interventions or long-term medication use. Patients typically experience little to no downtime, allowing for a quicker return to daily activities.

More research is still needed to figure out the best amount, how often, and what happens in the long run with PRP therapy for knee OA. But right now, the evidence we have says it’s a really good option for treating it. As we learn more about how regenerative medicine works, PRP therapy seems like it could totally change how we deal with knee osteoarthritis. That means patients with knee problems might have a better chance at moving around and living life to the fullest.

What is knee osteoarthritis?

Ans: Knee osteoarthritis happens when your knee joint starts to wear out. It happens because the cushiony stuff inside your knee, called cartilage, gets worn down. This makes your knee hurt, feel stiff, and makes it harder to move around.

What are the risk factors for developing knee osteoarthritis?

Ans: Risk factors include ageing, being overweight or obese, previous knee injuries, repetitive stress on the knees, genetics, and certain occupations or sports that involve kneeling, squatting, or heavy lifting.

How can knee osteoarthritis be diagnosed?

Ans: When diagnosing a knee problem, doctors usually start by checking your knee, asking about your past health, and sometimes taking pictures of your knee using X-rays or MRI machines to see what’s going on inside.

What are the potential complications of knee osteoarthritis?

Ans: Knee osteoarthritis can cause a lot of problems like constant pain, difficulty moving around, weak muscles, funny-shaped joints, swelling, extra fluid, bumpy bones, loose ligaments, less cartilage, and falling more often. It can make it hard to do stuff and might mean needing surgery to fix your knee. 

What are the common symptoms of knee osteoarthritis?

Ans: Common symptoms of knee osteoarthritis include pain, stiffness, swelling, and decreased range of motion. Patients may experience difficulty walking, climbing stairs, or standing for prolonged periods. Joint tenderness and a grating sensation known as crepitus may also occur. Symptoms often worsen with activity and improve with rest.

After undergoing Platelet-Rich Plasma (PRP) treatment for knee osteoarthritis, patients often report significant improvements in their condition. Here are six notable enhancements commonly observed:

• Pain Reduction: PRP therapy can lead to a substantial decrease in knee pain, enabling individuals to perform daily activities with greater ease and comfort. Many patients experience relief from chronic pain that had previously limited their mobility.
• Increased Mobility: Patients typically notice improved joint function and flexibility following PRP treatment. Enhanced mobility allows individuals to engage in physical activities they may have previously avoided due to knee discomfort.
• Reduced Inflammation: PRP injections have been shown to decrease inflammation in the affected knee joint, resulting in reduced swelling and tenderness. This reduction in inflammation contributes to overall pain relief and improved joint function.
• Enhanced Healing: PRP therapy promotes the body’s natural healing process by delivering concentrated platelets to the damaged tissues in the knee joint. This accelerated healing can lead to faster recovery times and improved overall joint health.
• Long-lasting Effects: Many patients experience long-lasting benefits from PRP treatment, with improvements in symptoms persisting for months or even years after the procedure. This long-term relief can significantly improve the quality of life for individuals with knee osteoarthritis.
• Minimally Invasive: Compared to surgical interventions, PRP therapy is minimally invasive and typically involves minimal discomfort and downtime. This outpatient procedure offers a non-surgical alternative for managing knee osteoarthritis, making it an attractive option for many patients seeking relief from their symptoms.

Platelet-rich plasma (PRP) therapy is a new thing for treating bad knees because of arthritis. It’s all about using your own blood to help your knee feel better without needing big surgeries. It’s like giving your knee a natural boost to feel better and maybe even fix itself a bit. The mechanism of PRP treatment involves several steps:

• Blood Collection: The process begins with the extraction of a small sample of the patient’s blood, usually from the arm. This sample is then centrifuged to separate the platelets from other blood components.
• Platelet Activation: Once separated, the concentrated platelets are activated to release growth factors and cytokines, such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and interleukins. These bioactive substances play crucial roles in tissue repair, inflammation modulation, and cell proliferation.
• Injection Preparation: The activated PRP is then prepared for injection into the affected knee joint. In some cases, it may be combined with local anaesthetics or other agents to enhance its effectiveness.
• Injection Procedure: A healthcare professional administers the PRP injection directly into the knee joint under sterile conditions and guided by imaging techniques like ultrasound to ensure precision and accuracy.
• Tissue Repair and Regeneration: Upon injection, the growth factors and cytokines released from the activated platelets initiate a cascade of biological processes. They stimulate the repair of damaged cartilage, reduce inflammation, and promote the regeneration of healthy tissue within the knee joint.
• Symptom Relief and Functional Improvement: Over time, patients typically experience relief from pain, stiffness, and swelling associated with knee osteoarthritis. PRP therapy may also improve joint function, mobility, and overall quality of life, offering a conservative yet effective alternative to more invasive treatments like surgery.
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